★★★★★
★★★★★
Verified Buyer
You guys are great! Thanks!
Uso del prodotto: Questo prodotto è destinato esclusivamente alla ricerca.
Tutte le informazioni sui prodotti presenti su questo sito hanno scopo esclusivamente educativo. Qualsiasi forma di introduzione nel corpo di esseri umani o animali è severamente vietata dalla legge. Questo prodotto deve essere maneggiato solo da professionisti abilitati e qualificati. Non è un farmaco, un alimento o un cosmetico e non deve essere etichettato, utilizzato o presentato come tale.
Purezza del 99% garantita
Solo per uso di ricerca
Checkout sicuro
IGF-1 DES 1 mg
IGF-1 DES (Des(1-3)IGF-1) is a naturally occurring, endogenous truncated form of IGF-1 lacking the first three N-terminal amino acids.
$55.95 – $559.50
Stessa formula affidabile. Nuovo look.
Durante il cambio di confezione potresti ricevere prodotti con l’etichetta precedente o con quella nuova. Formulazione, purezza e qualità restano esattamente le stesse, secondo i nostri standard.
Metodi di pagamento accettati
- Carta di credito
- Bonifico bancario (SEPA istantaneo)
- Bonifico bancario (ACH)
- Wise
- Revolut
- Zelle
- Remitly
- Western Union
- Chime
- Altri metodi
-25% su tutto – fino al 31 Ottobre
25% sui prezzi ordinari, in sostituzione degli altri saldi. Cumulabile solo con lo sconto crypto.
Spedizione
Spedizione in giornata per gli ordini USA effettuati entro le 12:00 EST.
Vedi le condizioni di spedizione →Testato in laboratorio
Ogni lotto è testato per purezza, potenza e qualità.
Vedi i risultati di laboratorio →IGF-1 DES (Des(1-3)IGF-1) is a naturally occurring, endogenous truncated form of IGF-1 lacking the first three N-terminal amino acids. This truncation reduces IGFBP affinity by approximately 10-fold relative to native IGF-1 while modestly increasing IGF-1 receptor binding potency.
The shorter half-life and higher local potency of IGF-1 DES make it a useful research tool for studying IGF-1R activation dynamics distinct from the longer-acting IGF-1 LR3 analogue.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
All Biotech Peptides products are independently third-party tested at a USA-based HPLC-licensed laboratory prior to distribution. Certificates of Analysis (COA) are published on the Independent Test Results page and available at product level. If any independently conducted HPLC test returns a negative result, Biotech Peptides will refund: (1) the cost of the HPLC test, and (2) the full order amount including shipping.
| Chemical Formula | C319H501N91O96S7 |
|---|---|
| Synonyms | IGF1 Human Des1-3; Insulin-Like Growth Factor 1 Des (1-3) Human Recombinant; Somatomedin C; IGF-I; IGFI; IGF1; IGF-IA; Des(1-3); Des1-3; Des 1-3; Des (1-3); IGF-1 (4-70); IGF1 Des1-3 |
| Molar Mass | 7,649 g/mol |
| CAS Number | 112603-35-7 |
| Total Compound Content | 1 mg per vial |
| Shelf Life | 36 months |
IGF-1 DES is a truncated analogue of insulin-like growth factor 1 (IGF-1) in which the three N-terminal amino acids are absent relative to the full-length peptide. This structural modification alters its interaction profile with insulin-like growth factor binding proteins (IGFBPs), resulting in a greater proportion of unbound peptide available for receptor interaction. IGF-1 DES retains high-affinity binding to the insulin-like growth factor 1 receptor (IGF-1R) and preserves activation of downstream receptor-mediated signaling pathways, including PI3K/Akt/mTOR and MAPK/ERK cascades. The modified structure and distinct receptor-accessibility profile make IGF-1 DES a valuable research tool for investigating IGF-1R pharmacology, ligand-receptor interactions, growth factor signaling mechanisms, and comparative studies of IGF-1 analogues. Supplied as a lyophilized preparation (1 mg/vial). Independently third-party HPLC-tested; COA available per batch.
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
How does IGF-1 DES differ from IGF-1 LR3 in terms of receptor interaction characteristics?
IGF-1 DES and IGF-1 LR3 are structurally modified forms of IGF-1 that differ in their interactions with insulin-like growth factor binding proteins (IGFBPs) and their resulting receptor-accessibility profiles. IGF-1 DES utilizes N-terminal truncation, whereas IGF-1 LR3 incorporates amino acid substitution and sequence extension.
These structural differences make both compounds useful research tools for investigating IGFBP interactions, ligand-receptor dynamics, and comparative IGF-1 receptor pharmacology.
What distinguishes IGF-1 DES from full-length IGF-1?
IGF-1 DES is a truncated analogue of IGF-1 in which the N-terminal region has been modified relative to the full-length peptide. This structural change alters its interaction characteristics while preserving high-affinity binding to the insulin-like growth factor 1 receptor (IGF-1R).
As a result, IGF-1 DES is frequently used in studies examining structure-function relationships, receptor activation mechanisms, and the influence of peptide architecture on growth factor signaling pathways.
Why is IGF-1 DES useful for growth factor signaling research?
IGF-1 DES retains activation of key IGF-1R-mediated signaling pathways, including PI3K/Akt/mTOR and MAPK/ERK regulatory cascades. Its modified structure and distinct interaction profile make it a valuable research tool for investigating ligand-receptor interactions, growth factor signaling mechanisms, receptor pharmacology, and comparative studies of IGF-1 analogues and related signaling systems.
Customer Reviews (10)
★★★★★
★★★★★
5 / 5
★★★★★
★★★★★
Verified Buyer
This co has a great customer service and great DES. I will be ordering again. Tnx!
★★★★★
★★★★★
Verified Buyer
Great Product! Good Price! Fast Delivery! Doesn't get any better.
★★★★★
★★★★★
Verified Buyer
I had a query relating to the delivery of the item. My question was answered within minutes with a very helpful response. The item were very carefully packaged and neatly arranged. Will definately be using IGF-1 DES 1MG again.
★★★★★
★★★★★
Verified Buyer
Very happy with the product
★★★★★
★★★★★
Verified Buyer
We got fantastic research results. Highly recommend the prompt communication, the chemical quality is top notch. Great value.
★★★★★
★★★★★
Verified Buyer
Great quality on the support team and it's an exceptionally pure batch. Highly consistent test results. Highly recommend this vendor.
★★★★★
★★★★★
Verified Buyer
Top-notch quality from the customer service and quality was great and dispatch was incredibly fast. My laboratory research results exceeded expectations. Excellent all-round service.
★★★★★
★★★★★
Verified Buyer
Super happy with the super fast shipping, the compound is pure and high quality. Our research results are completely exceeding expectations. Excellent all-round service.
★★★★★
★★★★★
Verified Buyer
Service is an impressive and higher standard. I would love to re-order soon.
