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S4 (Andarine) 25mg/capsule, 60 caps
S4 (Andarine, GTx-007) is a propanamide-class non-steroidal selective androgen receptor modulator (SARM) originally developed as a high-affinity androgen receptor (AR) ligand.
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S4 (Andarine, GTx-007) is a propanamide-class non-steroidal selective androgen receptor modulator (SARM) originally developed as a high-affinity androgen receptor (AR) ligand. It functions as a partial agonist at AR and has been characterized by its differential transcriptional activation profile across distinct androgen receptor signaling systems. Experimental investigations have demonstrated selective modulation of AR-mediated gene expression and receptor-cofactor interactions, distinguishing S4 from full androgen receptor agonists. Research applications include androgen receptor pharmacology, AR partial agonism studies, receptor-mediated transcriptional regulation, ligand-receptor interaction analysis, and structure-activity relationship investigations involving non-steroidal SARM scaffolds.
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3D Molecular Structure
Drag to rotate · scroll to zoomSelect12.5mg/100tabs | 25mg/60 capsules
| Chemical Formula | C19H18F3N3O6 |
|---|---|
| Synonyms | Andarine, 401900-40-1, GTX-007, (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide, GTX00 |
| Molar Mass | 441.4 g/mol |
| CAS Number | 401900-40-1 |
| PubChem CID | 9824562 |
| Total Compound Content | 1,500 mg (25 mg per capsule) |
| Shelf Life | 36 months |
S4 (Andarine) is a propanamide-class non-steroidal selective androgen receptor modulator (SARM) developed as a high-affinity androgen receptor (AR) ligand. AR binding affinity is in the low nanomolar range, and the compound functions as a partial agonist of the androgen receptor, producing a distinct receptor-mediated transcriptional profile through differential co-activator recruitment and selective modulation of AR-dependent gene expression pathways. These characteristics distinguish S4 from full androgen receptor agonists and have established it as a valuable research tool for investigating androgen receptor pharmacology, receptor-cofactor interactions, and transcriptional regulation mechanisms.
Experimental investigations have examined the relationship between S4 and AR-mediated signaling networks, ligand-receptor binding dynamics, and pathway-specific regulatory systems associated with androgen receptor activation. Research applications include AR partial agonism studies, receptor pharmacology, structure-activity relationship investigations, transcriptional control mechanisms, and mechanistic evaluation of non-steroidal androgen receptor modulators. Supplied in 25 mg capsules. Independently third-party HPLC-tested; COA available per batch.
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
What distinguishes S4 (Andarine) from other androgen receptor modulators?
S4 is a propanamide-class non-steroidal androgen receptor modulator characterized by partial agonist activity at the androgen receptor (AR). Unlike full AR agonists, S4 produces a distinct receptor-mediated transcriptional profile through differential co-activator recruitment and selective modulation of AR-dependent gene expression pathways.
These characteristics make it a valuable research tool for investigating partial agonism, receptor pharmacology, and androgen receptor-mediated signaling mechanisms.
How does S4 compare to other non-steroidal androgen receptor modulators in research applications?
A: S4 belongs to a chemically distinct non-steroidal scaffold class and exhibits a well-characterized androgen receptor interaction profile. Comparative investigations frequently utilize S4 alongside other AR modulators to examine differences in receptor binding characteristics, co-regulator interactions, transcriptional responses, and structure-activity relationships.
Its extensive characterization has established it as a widely referenced compound in androgen receptor pharmacology research.
Why is S4 useful for androgen receptor signaling studies?
S4 has been extensively investigated as a model compound for examining androgen receptor activation, receptor-cofactor interactions, and downstream transcriptional regulation. Experimental studies have explored its effects on AR-mediated signaling networks, ligand-receptor binding dynamics, and pathway-specific regulatory systems.
These properties make S4 a useful research tool for studies of androgen receptor biology, transcriptional control mechanisms, and non-steroidal receptor modulator pharmacology.
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Exceptional service on the service. In addition, the product is of excellent quality. My laboratory research results exceeded expectations. Will buy again.
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I'm very happy with the prompt communication, the compound is pure and high quality. A trustworthy supplier. Results from my tests exceeded all expectations.
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Our research results have been outstanding. Outstanding experience with how fast it shipped. happy with the quality of this compound. Thanks for the outstanding support!
